diff --git a/.circleci/config.yml b/.circleci/config.yml
index ba498cd4d1..689f31fc81 100644
--- a/.circleci/config.yml
+++ b/.circleci/config.yml
@@ -158,7 +158,12 @@ jobs:
       - run:
           name: Run E2E Tests for macOS
           command: |
-            pnpm nx affected -t e2e-macos-ci --parallel=1 --base=$NX_BASE --head=$NX_HEAD
+            HAS_CHANGED=$(node ./scripts/check-react-native-changes.js $NX_BASE $NX_HEAD);
+            if $HAS_CHANGED; then
+              pnpm nx affected -t e2e-macos-ci --parallel=1 --base=$NX_BASE --head=$NX_HEAD
+            else
+              echo "Skip E2E tests for macOS as there are no changes in React Native projects."
+            fi
           no_output_timeout: 45m
 
 # -------------------------
diff --git a/scripts/check-react-native-changes.js b/scripts/check-react-native-changes.js
new file mode 100644
index 0000000000..5723339bbd
--- /dev/null
+++ b/scripts/check-react-native-changes.js
@@ -0,0 +1,6 @@
+const nxBase = process.argv[2];
+const nxHead = process.argv[3];
+const gitDiffCount = require('child_process').execSync(
+  `git diff --name-only ${nxBase} ${nxHead} | (grep -E 'packages/detox|packages/react-native|packages/expo|e2e/detox|e2e/react-native|e2e/expo' || true) | wc -l`
+);
+console.log(parseInt(gitDiffCount.toString()) > 0);